Tissue Engineering & Regenerative Medicine
Dr Dimitrios Zeugolis
functional biomaterials; tissue engineering & regenerative medicine; collagen-based biomaterials; cell-sheet tissue engineering; fibrosis; scarring; drug delivery; gene delivery;
Fibrosis of liver and lung, for example, currently ranks 25th in terms of global disease burden. Antifibrotic drug development has failed to deliver a functional therapy, primarily due to the inadequate in vitro models. Our research aims to develop an in vitro fibrosis model and assess the efficacy of the model using nano-carriers loaded with antifibrotic molecules (e.g. drugs, genes).