MedDevDoc Research Areas

‌1. Biomaterials and Drug Delivery Devices

Controlled delivery of therapeutic molecules to injured tissue remains one of the most significant challenges facing the translation of novel drug therapeutics. These developed chemistries are being processed for clinical application and integration into medical devices to provide selective drug delivery strategies. CÚRAM's expertise in applying biomaterials to disease targets extends from target identification and lead optimisation, formulation design, physicochemical characterisation, toxicity testing, and bioavailability to efficacy in preclinical models.

2. MedTech AI, Machine Learning, Medical Imaging and Soft Robotics

Machine learning is becoming an invaluable tool for medical device research, given its ability to enhance the speed and accuracy of computational models, extensive data management, and high-performance computing. Hence, they are available to researchers and clinicians to enable better real-time predictions for more accurate results and diagnostics. Radical new techniques, such as soft robotics, are beginning to be used to create bio-inspired designs for devices with implications for various medical applications.

3. Immuno Engineering

Tissue Engineering and Regenerative Medicine is a crucial area of research at CÚRAM to find solutions to chronic health problems and conditions of medical needs. Scientific advances in stem cells, gene therapy, biomaterials, medical device technology, growth and differentiation factors, and biomimetic environments have created unique opportunities to fabricate tissues in the laboratory from combinations of engineered extracellular matrices ("scaffolds"), cells, and biologically active molecules. With a focus on biomimetics and regenerative medicine, CÚRAM is developing innovative approaches, assays, and tools for comprehensive and accurate analysis of complex biological systems and their interaction with medical devices and associated therapeutics. 

4. Medical and Drug Delivery Devices as Applied to Neurodegenerative Diseases

Controlled delivery of therapeutic molecules to neuro-injured tissue is one of the most significant challenges facing the translation of novel drug therapeutics. These developed chemistries are being processed for clinical application and integration into medical devices to provide selective drug delivery strategies for neural discords. CÚRAM's expertise in applying biomaterials to disease targets extends from target identification and lead optimisation, formulation design, physicochemical characterisation, toxicity testing, and bioavailability to efficacy in preclinical models.