Mark Skylar Scott

Scaling 3D bioprinting Towards Whole Organ Biomanufacturing

Speaker: Mark Skylar-Scott

Location: Biomedical Sciences Building, University of Galway

Date: Monday, 21st July 2025

We are pleased to welcome Dr Mark Skylar-Scott from Stanford University to speak at CÚRAM as part of our seminar series.

Mark Skylar-Scott is an Assistant Professor of Bioengineering at Stanford, a member of the Basic Science and Engineering Initiative at the Children’s Heart Centre and a Chan-Zuckerberg Biohub Investigator. His laboratory focuses on the scaling-up of 3D bioprinting technologies with applications in cardiac tissue engineering to cure congenital heart defects.

His approaches emphasise scaling stem cell production and differentiation and tissue vascularisation and maturation to bring tissue engineering from microscopic tissues in the Petri dish towards kilograms of viable and functional organs. He has received the NIH Director’s New Innovator Award and an ARPA-H Award to support the development of new 3D printing hardware, wetware, and software to accelerate cardiovascular tissue engineering.

In this talk, Mark will highlight recent advances in bioprinting that are unlocking the third dimension of tissue engineering, enabling tissues that are thick, viable, and replete with vascular networks. Finally, Dr Skylar-Scott will describe their efforts towards scaling up cell and organoid production in automated litre-scale bioreactors and their rheological behaviour when these organoids are compacted into a printable paste. Now leveraging an award from ARPA-H, their large-scale cell manufacturing, bioprinting, and tissue vascularisation efforts are converging to form a pathway towards the production of a whole human heart.

The event is hosted by Andrew Daly.

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