Christos Tapeinos

Selective Targeting of Cancerous Microenvironments with Lipid-Based Nanosystems

Speaker: Christos Tapeinos

Location: Biomedical Sciences Building, University of Galway

Date: Thursday, 4th September 2025

CÚRAM is pleased to host a seminar featuring Christos Tapeinos from the University of Manchester.

The talk will focus on lipid-based nanoparticles (LNPs) as a strategy for selectively targeting cancerous microenvironments, with particular emphasis on overcoming biological barriers such as the blood–brain barrier (BBB) in brain cancer and the desmoplastic stroma in pancreatic cancer. One of the key strategies of treating complex diseases like cancer lies in the ability of LNPs to interact with tumour cells and their surrounding microenvironment, facilitating its reconfiguration. Dr Tapeinos will discuss methods to enhance the selective targeting of LNPs to tumour sites, improving their navigation of these barriers and interaction with the tumour microenvironment, ultimately increasing therapeutic efficacy.

Dr Christos Tapeinos is a Lecturer in Pharmaceutical Sciences at the Division of Pharmacy and Optometry, University of Manchester. His research focuses on developing smart nanomedicines and drug delivery systems for brain diseases such as brain cancer, neurodegeneration, and pancreatic cancer. He is particularly interested in the interactions between nanoparticles and the tumour microenvironment, and in using fluidic models that mimic healthy and diseased tissues to improve therapeutic selectivity and overcome biological barriers.

All are welcome to attend.

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